Fine needle aspiration of breast myofibroblastoma - A case report

BACKGROUND: The use of fine needle aspiration cytology (FNAC) for the diagn osis of breast diseases in men has received little attention. We report the cytologic and histologic findings of myofibroblastoma of the breast ill a 52-year-old man. CASE: Smears disclosed irregular and cohesive sheets of cells, with ill-def ined cytoplasm and oval nuclei containing single nucleoli. The nuclear memb rane was frequently quently grooved, and occasional intranuclear cytoplasmi c inclusions (pseudoinclusions) were also found. The background was clean a nd contained scarce collagenous stroma and fragments of myxoid material. To the best of our knowledge, there have been only seven previous reports of breast myofibroblastoma in which the cytologic features are well documented , and none of them mention the presence of pseudoinclusions. CONCLUSION: FNAC could suggest the diagnosis of this distinctly uncommon tu mor if evaluated together with the clinical and radiologic findings.