Clinical studies have shown that certain probiotics may be useful in treati
ng a variety of diarrheal disorders, including rotavirus diarrhea, antibiot
ic-associated diarrhea, Clostridium difficile diarrhea, and traveler's diar
rhea. New data suggest that probiotics might be useful in controlling infla
mmatory diseases, treating and preventing allergic diseases, preventing can
cer, and stimulating the immune system, which may reduce the incidence of r
espiratory disease. Different modes of administering probiotics are current
ly being investigated, which may ultimately lead to the widespread use of p
robiotics in functional foods. It is important that such practices be direc
ted by carefully controlled clinical studies published in peer-reviewed jou
rnals.