Purpose: To evaluate the effectiveness of a "one-bottle" dentin adhesive fo
r reducing or eliminating hypersensitivity in exposed cervical dentin. Mate
rials and Methods: Eight patients with hypersensitive teeth were enrolled i
n this clinical trial. The hypersensitive teeth included a total of 22 prem
olars and anterior teeth with exposed cervical dentin that was sensitive to
cold or other stimuli. A single layer of Prime & Bond 2.1, an acetone-base
d "one-bottle" adhesive, was applied to the cervical dentin and was light-c
ured. Sensitivity to compressed air and cold stimuli was determined immedia
tely before and after treatment, and at periods ranging to 24 wks after tre
atment. Patient responses to the stimuli were timed, and were also evaluate
d by the use of a visual analogue scale. Results: Application of a single c
oat of Prime & Bond 2.1 significantly reduced cervical dentin hypersensitiv
ity to both compressed air and cold stimuli immediately after treatment. Th
e reduction in hypersensitivity remained significant at 24 wks after treatm
ent.