Granulomatous kerato-conjunctivitis as a manifestation of Hodgkin lymphoma

PURPOSE: To report atypical kerato-conjunctivitis as a manifestation of Hod gkin disease. METHODS: Case report. RESULTS: A 19-year old woman presented with conjunctival nodules and cornea l infiltrates. Diffuse lymph node enlargement occurred, but not in the prea uricular or submandibular areas. Extensive microbiologic examination was ne gative. Conjunctival biopsy showed noncaseating granulomas. Inguinal lymph node biopsy showed Hodgkin lymphoma, and chemotherapy was instituted. Ocula r signs resolved after 6 weeks, but a corneal scar remained. CONCLUSIONS: The appearance of conjunctival granulomas and corneal infiltra tes may represent a clinical manifestation of Hodgkin lymphoma. (Am J Ophth almol 2001;131:796-797. (C) 2001 by Elsevier Science Inc. All rights reserv ed.).