Membrane fusion induced by phospholipase C and sphingomyelinases

Authors
Goni, FM Alonso, A
Citation
Fm. Goni et A. Alonso, Membrane fusion induced by phospholipase C and sphingomyelinases, BIOSCI REP, 20(6), 2000, pp. 443-463
Citations number
71
Categorie Soggetti
Cell & Developmental Biology
Journal title
BIOSCIENCE REPORTS
ISSN journal
01448463 → ACNP
Volume
20
Issue
6
Year of publication
2000
Pages
443 - 463
Database
ISI
SICI code
0144-8463(200012)20:6<443:MFIBPC>2.0.ZU;2-0
Abstract
In the past decade lipid vesicle fusion induced by either bacterial PC-pref erring phospholipase C, phosphatidylinositol-specific phospholipase C, sphi ngomyelinase, or a combination of phospholipase C and sphingomyelinase has been demonstrated. In the present paper, the experimental evidence is revie wed, and discussed in terms of the underlying molecular mechanisms of fusio n, and of the possible physiological relevance of these findings.