Interhemispheric relay time (IHRT) is inferred from simple (visual) reactio
n time (SRT) by subtracting SRTs in ipsilateral hand-field conditions from
SRTs in contralateral hand-field conditions. This index, the "crossed-uncro
ssed differential" (CUD) is a synonym of IHRT in the current literature. Th
e CUD has been shown to be significantly moderated by experimental variable
s, including attentional. One reason the CUD = IHRT hypostasy persists toda
y is that no experimental manipulation has yet been able to generate a sign
ificantly negative CUD in a subject manifesting a significant positive CUD
in classical conditions. We implemented an experimental manipulation, in SR
T. consisting of increasing complexity of the response after the initial ke
y press required at detection. In a very large scale single-case experiment
, we found that the CUD thus went from significantly positive in classical
SRT to significantly negative in the increased response load condition. (C)
2001 Academic Press.