Often used in cognitive studies measuring reaction times and in functional
imaging studies, the subtraction paradigm is based on the comparison of per
formance on tasks presupposed to refer to different cognitive levels of pro
cessing. Within the framework of the study of phonological processing of wo
rds, manipulating the grapheme-phoneme transparency of stimuli can represen
t a means of counteracting the methodological drawbacks inherent to the sub
traction paradigm. Thus, the purpose of this study was to determine the eff
ect of the level of difficulty of grapheme-phoneme matching on the processi
ng of transparent and nontransparent words. Grapheme-phoneme matching was c
arried out both on the final syllable of words and on sublexical segments w
ithin the word. The results indicate that processing is faster for the tran
sparent than for the nontransparent stimuli. This task will now have to he
reintroduced in brain imaging studies aiming to look at different levels of
difficulty for grapheme-phoneme matching. (C) 2001 Academic Press.