Use of measures of endothelial function to stratify risk

Measures of endothelial dysfunction can be used to stratify risk in coronar y artery disease and diabetes. Two studies are reviewed in which endothelia l dysfunction was shown to be associated with an increased risk of cardiova scular events and to predict long term atherosclerotic disease. A study tha t showed reduced microvascular and macrovascular reactivity in subjects at risk for type 2 diabetes, and a study indicating that endothelial dysfuncti on precedes the development of microalbuminuria in type 1 diabetes are revi ewed.