Asymmetric addition of diethyl zinc to aldehyde catalyzed by chiral Ti(IV)/Schiff base polymer

Authors
Dong, CE Zhang, JL Zheng, WZ Zhi, YG Zhang, LF Yu, ZL
Citation
Ce. Dong et al., Asymmetric addition of diethyl zinc to aldehyde catalyzed by chiral Ti(IV)/Schiff base polymer, CHEM J CH U, 22(5), 2001, pp. 779-782
Citations number
7
Categorie Soggetti
Chemistry
Journal title
CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE
ISSN journal
02510790 → ACNP
Volume
22
Issue
5
Year of publication
2001
Pages
779 - 782
Database
ISI
SICI code
0251-0790(200105)22:5<779:AAODZT>2.0.ZU;2-I
Abstract
New Schiff base chiral polymers was synthesized. The asymmetric addition of diethyl zinc to aldehyde was achieved catalyzed by Ti(IV)/polymer which wa s formed in situ from chiral polymer and Ti(O-i-Pr)(4). Optical alcohols we re obtained in a high yield with e.e. up to 84.5%, The effects of temperatu re, complex time, structure of substrate etc. on the catalytic activity and enantio selectivity were studied in detail. The reaction mechanism was pro posed.