42,43,44,45,46,47,55-Heptanor-41-oxohomoyessotoxin, a new biotoxin from mussels of the northern Adriatic sea

Authors
Ciminiello, P Fattorusso, E Forino, M Poletti, R
Citation
P. Ciminiello et al., 42,43,44,45,46,47,55-Heptanor-41-oxohomoyessotoxin, a new biotoxin from mussels of the northern Adriatic sea, CHEM RES T, 14(5), 2001, pp. 596-599
Citations number
14
Categorie Soggetti
Pharmacology & Toxicology
Journal title
CHEMICAL RESEARCH IN TOXICOLOGY
ISSN journal
0893228X → ACNP
Volume
14
Issue
5
Year of publication
2001
Pages
596 - 599
Database
ISI
SICI code
0893-228X(200105)14:5<596:4ANBFM>2.0.ZU;2-D
Abstract
The diarrhetic shellfish toxin composition in the digestive glands of musse ls from the northern Adriatic sea was investigated. Along with known yessot oxins, identified by comparison of their chromatographic and spectral prope rties with those reported in the literature, we isolated a new analogue of yessotoxin, 42,43,44,45,46,47,55-heptanor-41-oxohomoyessotoxin, 1. Its stru cture was determined by H-1 NMR spectroscopy and mass spectrometry.