The covalent casting of one-dimensional hydrogen bonding motifs: Toward oligomers and polymers of predefined topography

The covalent casting of noncovalent architectures serves to define large co valent constructs that express well-defined modes of aggregation. In the ca se of one-dimensional hydrogen-bonding motifs, covalent casting yields mole cular strands that adopt a duplex mode of aggregation. The effectiveness of this design principle is illustrated through the casting of the aminotriaz ine hydrogen-bonding motif. These studies have led to the conception of a n ew family of topographically defined oligomers, which, akin to DNA, self-as semble in the form of a duplex through the action of interstrand hydrogen b onds.