M. Pisarcik et al., Aggregates of sodium hyaluronate with cationic and aminoxide surfactants in aqueous solution - light scattering study, COLL SURF A, 183, 2001, pp. 555-562
Citations number
36
Categorie Soggetti
Physical Chemistry/Chemical Physics
Journal title
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
Aggregation properties of sodium hyaluronate (NaHA) with different types of
surfactants in aqueous sodium chloride solution have been studied by using
static and dynamic light scattering method. Molecular weight, second viria
l coefficient, radius of gyration, and hydrodynamic radius have been calcul
ated. The polymer - surfactant aggregate growth was found in complexes of N
aHA with an ionic surfactant (dodecyltrimethylammonium bromide) and ionic,
dimeric surfactants (dodecanediyl-alpha,omega -bis(dimethyloctylammonium br
omide) and N,N ' -bis(dodecyldimethyl)-4, 13-dioxo-3,14-dioxahexadecane-1,1
6-diyldiammonium dibromide). In case of dodecyldimethylamine oxide (DDAO),
the decreasing molecular weight and aggregate size of the NaHA - DDAO compl
ex with increasing DDAO concentration were found above the surfactant criti
cal micelle concentration, indicating the absence of electrostatic interact
ions between NaHA and DDAO that would lead to the increase in aggregate siz
e. This behaviour may be ascribed to the non-ionic character of DDAO. (C) 2
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