Toxicology: Statistical perspectives

Authors
Citation
Pk. Sen, Toxicology: Statistical perspectives, CURRENT SCI, 80(9), 2001, pp. 1167-1175
Citations number
22
Categorie Soggetti
Multidisciplinary,Multidisciplinary
Journal title
CURRENT SCIENCE
ISSN journal
00113891 → ACNP
Volume
80
Issue
9
Year of publication
2001
Pages
1167 - 1175
Database
ISI
SICI code
0011-3891(20010510)80:9<1167:TSP>2.0.ZU;2-Z
Abstract
Toxicity abounds in nature, environment, and in our modern life-style. Toxi cology relates to the study of the intake process of such toxins by human b eing, their mode of propagation, biological reactions, molecular level of p enetration, genotoxicity and aftermaths, Because of the latent nature of a large class of toxic substances, the extreme variability of human metabolis m as well as their exposure to toxic material, yet unknown nature of many c arcinogenic activities, and immense difficulties in the assessment of effec tive toxicity levels (especially in the environment), there is a genuine ne ed to have statistical appraisal at each phase. These statistical perspecti ves are highlighted here along with some outline of recent statistical appr oaches in this much needed assessment task.