S. Kurtoglu et al., 5-HYDROXY-3-INDOLE ACETIC-ACID LEVELS IN INFANTILE COLIC - IS SEROTONINERGIC TONUS RESPONSIBLE FOR THIS PROBLEM, Acta paediatrica, 86(7), 1997, pp. 764-765
Levels of 5-hydroxy-3-indole acetic acid (5-OH IAA), a metabolite of s
erotonin, were studied in infants with infantile colic in order to inv
estigate the aetiology of infantile colic pathogenesis. The study incl
uded 16 patients with infantile colic and 10 control subjects. Random
urinary 5-OH IAA levels of colicky infants were found to be higher tha
n those in the control group. This finding suggested that high seroton
in levels may be responsible for infantile colic.