Endometrial receptivity in terms of pinopode expression is not impaired inwomen with endometriosis in artificially prepared cycles

Objective: To assess endometrial receptivity in terms of pinopode expressio n in women with endometriosis. Design: Prospective, observational study. Setting: Oocyte donation program at the Institute Valenciano de Infertilida d. Patient(s): Twelve women with endometriosis as the only cause of infertilit y. Intervention(s): Pinopode expression pattern analysis by scanning electron microscopy in two sequential endometrial biopsies obtained in the same cycl e of each patient. Main Outcome Measure(s): Pinopode pattern and pregnancy rates. Results(s): Pinopode expression in women with endometriosis did not differ from that of patients without endometriosis undergoing artificial cycles. S imilarly, the clinical outcome in these women was comparable to that of the general population included in the oocyte donation program. The pregnancy rate per transfer was 46.7%. Conclusion(s): These results show that in women with endometriosis undergoi ng oocyte donation under hormone replacement therapy, pinopode expression i s not altered, suggesting that endometrial receptivity in women with this d isease remains unaltered. (Fertil Steril(R) 2001;75:1231-3. (C) 2001 by Ame rican Society for Reproductive Medicine.).