Urethral condylomata. A therapeutic challenge

Background and Objective. Very diverse treatment recommendations exist in t he literature on HPV lesions of the urethra. There are no treatment guideli nes from the specialist societies. Both these factors have led to a very wi de spectrum of heterogeneous treatment strategies in hospitals and medical practices of various specialties. Primary and secondary treatment of urethr a I condylomata by practitioners as well as a specialized HPV center was ev aluated. Patients/Methods. One hundred and five patients with condylomata of the ure thra were studied. Most had been previously treated, often several times, b y a variety of specialists. We treated all regardless of prior treatment st atus with laser therapy. Results. A high percentage of patients treated with different methods in me dical practices but also at our high-technology center sometimes showed ser ious treatment complications and numerous recurrences. Most established met hods of treatment for condylomata on the external genitalia are not necessa rily applicable to the urethra. Conclusions. About 20% of urethral condylomata can only be reached by endos copy. Go-existing urethral malformations as well as complications of therap y are reasons for early cooperation with the urologist or HPV center.