SYNTHESIS OF SOME ABBREVIATED NAD(+) ANALOGS

Authors
HOCKOVA D HOLY A
Citation
D. Hockova et A. Holy, SYNTHESIS OF SOME ABBREVIATED NAD(+) ANALOGS, Collection of Czechoslovak Chemical Communications, 62(6), 1997, pp. 948-956
Citations number
12
Categorie Soggetti
Chemistry
Journal title
Collection of Czechoslovak Chemical Communications → ACNP
ISSN journal
00100765
Volume
62
Issue
6
Year of publication
1997
Pages
948 - 956
Database
ISI
SICI code
0010-0765(1997)62:6<948:SOSANA>2.0.ZU;2-6
Abstract
Four new ''abbreviated'' NAD(+) analogues with hydroxymethyl or carbox yl function as a substituent of an aliphatic chain linking the adenine and nicotinamide moieties were prepared using the Zincke reaction as the Ley step. As intermediates several new acyclic nucleoside analogue s containing hydroxy, carboxyl, azido and amino group were prepared.