The relationship between HA-1 compatability and the activation of helper Tlymphocyte precursors

Citation
V. Cukrova et al., The relationship between HA-1 compatability and the activation of helper Tlymphocyte precursors, IMMUNOBIOL, 203(4), 2001, pp. 699-704
Citations number
13
Categorie Soggetti
Immunology
Journal title
IMMUNOBIOLOGY
ISSN journal
01712985 → ACNP
Volume
203
Issue
4
Year of publication
2001
Pages
699 - 704
Database
ISI
SICI code
0171-2985(200105)203:4<699:TRBHCA>2.0.ZU;2-B
Abstract
The relationship between che compatibility in minor histocompatibility HA-1 antigen and the activation of helper (IL-2 producing) T lymphocyte precurs ors in vine was studied in the group of 17 HLA-A2 positive HLA identical si blings. Although the number of pairs studied is still small, no correlation has been found between HA-1 compatibility and helper T lymphocyte precurso rs activation. The results presented here could suggest the possibility tha t the HTLp assay does not have to be a relevant parameter for the detection of HA-l mismatches in HLA identical siblings.