GENERAL-METHOD FOR THE SYNTHESIS OF N-METHYL AMINO-ACIDS AND N-ALKYL AMINO ESTERS FROM ODONNELL SCHIFF-BASES

Authors
CHRUMA JJ SAMES D POLT R
Citation
Jj. Chruma et al., GENERAL-METHOD FOR THE SYNTHESIS OF N-METHYL AMINO-ACIDS AND N-ALKYL AMINO ESTERS FROM ODONNELL SCHIFF-BASES, Tetrahedron letters, 38(29), 1997, pp. 5085-5086
Citations number
21
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
29
Year of publication
1997
Pages
5085 - 5086
Database
ISI
SICI code
0040-4039(1997)38:29<5085:GFTSON>2.0.ZU;2-L
Abstract
N-methyl amino acids, including L-abrine, and N-alkyl amino esters, we re synthesized by reductive amination of O'Donnell's Schiff base amino esters with NaBH3CN and formaldehyde, or the appropriate aldehyde in CH3CN or THF in good to excellent yields, and with high purity. (C) 19 97 Elsevier Science Ltd.