Does renal transplantation increase the risk of breast diseases?

Purpose. To evaluate the risk of breast pathology occurrence in a group of kidney transplanted patients. Material and methods. In the last five years, 30 kidney-transplanted women underwent systematic breast evaluation in our institution and were included in this retrospective study (exposed-group). To compare with this exposed- group, 90 non transplanted women undergoing breast evaluation in the same p eriod at our institution (non-exposed group), were retrospectively randomiz ed. In both groups, results of breast evaluation were classified in two cat egories (normal and abnormal) and distribution of benign and malignant brea st pathologies were evaluated. The mean exposition-time was determined in m onths in the exposed-group. Comparative analysis of both groups included a comparaison of mean patients age and evaluation of the relative risk (RR) o f breast pathology occurrence. Results. Mean exposition time was 72.7 +/- 66.6 months. The percentages of benign breast pathology were 93.7% in the exposed-group and 83.3% in the no n-exposed group. Percentages of cancer were respectively 6.3 and 16.7%. Mea n patient age was quite similar in the exposed-group (50.7 +/- 10 years) an d in the non-exposed group (50.6 +/- 10.5 years). The relative risk of brea st pathology occurrence was 1.70 (0.99 < RR <2.91) and was not significant. Conclusion. In this retrospective series, no risk of breast pathology occur rence was demonstrated in a population of kidney-transplanted patients.