The economic impact of asthma is large and growing, and the use of economic
outcomes is increasing. Such outcomes serve as the basis for studies of th
e efficiency of care and are being reported increasingly as outcomes of cli
nical trials. This article presents the basic components of a cost-of-illne
ss study, the influences that have an impact on these components, the relat
ion of economic indicators to clinical outcomes, and the relative importanc
e of the economic factors for differing groups in society.