Formaldehyde release from ground root canal sealer in vitro

The formaldehyde release from three different ground root canal sealer mate rials was examined. Ten specimens each of AH26, Amubarut, and N2 were store d under dry conditions for 6 months. An amount of similar to 100 to 200 mg ground material was obtained from each sample by using a round bur and stor ed for 10 min in distilled water. The formaldehyde concentration of the imm ersion water was determined by high-performance liquid chromatography, The mean formaldehyde release per mg material was 6.6 (+/-2.5) mug for AH26 and 8.3 (+/-1.0) mug for Amubarut, A lower formaldehyde release was detectable by our method from the N2 samples (0.3 +/- 0.1 mug/g; p < 0.0001), in conc lusion formaldehyde release from ground root canal material is low, althoug h a risk of an allergic reaction in susceptible patients cannot be excluded .