Microfluidic systems with on-line UV detection fabricated in photodefinable epoxy

This paper describes a method for fabricating microfluidic devices in a pho todefinable epoxy (SU-8). This technique is compatible with, and complement ary to, conventional fabrication techniques. It allows microstructures form ed in SU-8 to be bonded to produce sealed microfluidic channels. A micromix er fabricated entirely in SU-8, using this technique, for performing liquid -phase reactions is shown to be suitable for visible spectroscopy. This fab rication method also allows the incorporation of materials that are often d ifficult to integrate. By fabricating hybrid devices that incorporate quart z windows, we demonstrate that these devices are compatible with organic so lvents and that in situ ultraviolet detection in a microfluidic system is p ossible.