A test of amino acid reversibility

Authors
Smith, NGC Eyre-Walker, A
Citation
Ngc. Smith et A. Eyre-walker, A test of amino acid reversibility, J MOL EVOL, 52(5), 2001, pp. 467-469
Citations number
12
Categorie Soggetti
Biology,"Experimental Biology
Journal title
JOURNAL OF MOLECULAR EVOLUTION
ISSN journal
00222844 → ACNP
Volume
52
Issue
5
Year of publication
2001
Pages
467 - 469
Database
ISI
SICI code
0022-2844(200105)52:5<467:ATOAAR>2.0.ZU;2-A
Abstract
In studies of molecular evolution, the assumption that protein evolution is reversible has often been made, but rarely tested. Here we use a large set of orthologous murid protein coding sequences to perform a simple test of reversibility, and find no evidence to reject the assumption of reversibili ty in protein evolution.