Purpose: To evaluate the role of MR imaging in the localisation of cer
ebrospinal fluid (CSF) fistulae. Material and Methods: A total of 36 c
onsecutive unselected patients with either clinically proven CSF leaka
ge (n=26) or suspected CSF fistula (n=10) were prospectively evaluated
by MR. All MR examinations included fast spin-echo T2-weighted images
in the 3 orthogonal planes. Thin-section CT was performed following e
quivocal or negative MR examination. MR and CT findings were correlate
d with surgical results in 33 patients. Results: CSF fistula was visua
lised as a dural-bone defect with hyperintense fluid signal continuous
with that in the basal cisterns on T2-weighted images. MR was positiv
e in 26 cases, in 24 of which the fistula was confirmed surgically. In
2 patients the CSF leakage was directly demonstrated on MR. MR sensit
ivity of 80% compared favourably with the reported 46-81% of CT cister
nography (CTC). No significant difference in MR sensitivity in detecti
ng CSF fistula was found between active and inactive leaks. Conclusion
: MR is recommended as the first investigation for detecting a CSF fis
tula owing to its efficacy and to its freedom from the potential compl
ications encountered with CTC.