Phenylnaphthalene compounds from the subterranean part of Vitex rotundifolia and their antibacterial activity against methicillin-resistant Staphylococcus aureus

Authors
Kawazoe, K Yutani, A Tamemoto, K Yuasa, S Shibata, H Higuti, T Takaishi, Y
Citation
K. Kawazoe et al., Phenylnaphthalene compounds from the subterranean part of Vitex rotundifolia and their antibacterial activity against methicillin-resistant Staphylococcus aureus, J NAT PROD, 64(5), 2001, pp. 588-591
Citations number
12
Categorie Soggetti
Agricultural Chemistry","Pharmacology & Toxicology
Journal title
JOURNAL OF NATURAL PRODUCTS
ISSN journal
01633864 → ACNP
Volume
64
Issue
5
Year of publication
2001
Pages
588 - 591
Database
ISI
SICI code
0163-3864(200105)64:5<588:PCFTSP>2.0.ZU;2-S
Abstract
A careful investigation of the subterranean part of Vitex rotundifolia has shown that this plant contains five novel lignans having a 1-phenylnaphthal ene-type skeleton together with four known lignans. These structures were e lucidated on the basis of spectroscopic data. Furthermore, some of the isol ated compounds showed antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA).