Structure revision and assignment of absolute stereochemistry of a marine C-21 bisfuranoterpene

Authors
Capon, RJ Jenkins, A Rooney, F Ghisalberti, EL
Citation
Rj. Capon et al., Structure revision and assignment of absolute stereochemistry of a marine C-21 bisfuranoterpene, J NAT PROD, 64(5), 2001, pp. 638-639
Citations number
9
Categorie Soggetti
Agricultural Chemistry","Pharmacology & Toxicology
Journal title
JOURNAL OF NATURAL PRODUCTS
ISSN journal
01633864 → ACNP
Volume
64
Issue
5
Year of publication
2001
Pages
638 - 639
Database
ISI
SICI code
0163-3864(200105)64:5<638:SRAAOA>2.0.ZU;2-V
Abstract
The C-21 bisfuranoterpene (-)-isotetradehydrofurospongin-1 (6), previously isolated from a Western Australian Spongia sp., has been reisolated from a specimen of Spirastrella papilosa collected during scientific trawling oper ations in the Great Australian Eight. A 2D NMR analysis of 6 has prompted r eassignment of the published structure 5, while degradation and chiral HPLC analysis have allowed determination of the absolute stereochemistry.