Ni. Bilous et al., LEUKEMIAS AND IMMUNOPHENOTYPICAL CHARACTE RISTICS OF HEMATOPOIETIC STEM-CELLS AND MYELOPOIESIS PROGENITOR CELLS, Eksperimental'naa onkologia, 19(2), 1997, pp. 83-95
Review of the data about the commitment and differentiation of early h
aematopoietic progenitor cells and changes in the expression of surfac
e antigens is presented. Phenotypic characteristic of different subpop
ulation of CD34(+)CDw90(+) cells, early progenitors of granulocytes, m
acrophages, erythroid and megakaryocytic cells (CFU-GEMM, CFU-GM, BFU-
E, CFU-E, CFU-Meg etc.) is given. Possible cell targets for malignant
transformation in leukemias are discussed.