The purpose of this study was to evaluate the recently proposed technique o
f He-3 prepolarization at low temperature and high field (Kober et al. Magn
Reson Med 1999; 41:1084-1087) for fast imaging of the lung. Helium-3 was c
ooled to 2.4 K in a magnetic field of 8 Tesla to obtain a polarization of 0
.26%, The polarized He-3 was warmed up to room temperature and transferred
to a rat, with a final polarization of about 0.1%, large enough for acquiri
ng a 3D image of the rat lung in 30 s. (C) 2001 Wiley-Liss, Inc.