This study was undertaken to validate a Norwegian translation of the Edinbu
rgh Postnatal Depression Scale (EPDS). The EPDS was validated against the D
SM-IV criteria for major depression, derived from the PRIME-MD, in an inter
view study of 56 women selected from a community-based questionnaire study
of 310 women 6 weeks postpartum. A score of greater than or equal to 10 on
the EPDS scale identified all women with major depression, giving a sensiti
vity of 100% (95% confidence interval; 72%-100%) and a specificity of 87% (
95% confidence interval; 77%-95%). The EPDS scores were strongly correlated
with the Montgomery-Asberg Depression Rating Scale in the subsample of wom
en interviewed (n = 56) and with the Hopkins Symptom Check List (SCL-25) sc
ores in the questionnaire study (n = 310). Our results with regard to the s
ensitivity and specificity estimates are comparable with prior validation s
tudies; however, the confidence intervals around the estimates are wide. Ne
vertheless, this study confirms that the EPDS is a valid clinical screening
instrument for detecting postpartum depression.