The Canon Autoref R-1 is used extensively to investigate aspects of the acc
ommodation response of the human eye. The measurement zone of the Autoref R
-1 is known to lie outside the central pupil and the instrument's readings
are therefore potentially influenced by the monochromatic aberrations of th
e eye. Since these aberrations are known to change as a function of accommo
dation, the error associated with the aberrations might influence the stimu
lus-response slope. We used masks and contact lenses with known amounts of
spherical aberration to establish the region of the pupil used by the Autor
ef R-1 in deriving a reading of the refractive power of the eye. This regio
n was estimated to be narrowly centred on a 3.5-mm diameter. The spherical
aberration of the eye was measured for five subjects across a range of acco
mmodation levels and used to predict the likely effect upon Autoref R-1 rea
dings. Positive spherical aberration will result in an apparent lead of acc
ommodation, while negative spherical aberration causes an apparent lag of a
ccommodation. For eyes with normal levels of spherical aberration, the slop
e of the stimulus-response will appear to be marginally flatter when measur
ed with the Autoref R-1. An example of an eye with coma-like aberrations is
also shown to produce Autoref R-1 results that will differ significantly f
rom more central refractive measurements. (C) 2001 The College of Optometri
sts. Published by Elsevier Science Ltd. All rights reserved.