Time-gated biological imaging by use of colloidal quantum dots

Authors
Dahan, M Laurence, T Pinaud, F Chemla, DS Alivisatos, AP Sauer, M Weiss, S
Citation
M. Dahan et al., Time-gated biological imaging by use of colloidal quantum dots, OPTICS LETT, 26(11), 2001, pp. 825-827
Citations number
9
Categorie Soggetti
Apllied Physucs/Condensed Matter/Materiales Science","Optics & Acoustics
Journal title
OPTICS LETTERS
ISSN journal
01469592 → ACNP
Volume
26
Issue
11
Year of publication
2001
Pages
825 - 827
Database
ISI
SICI code
0146-9592(20010601)26:11<825:TBIBUO>2.0.ZU;2-V
Abstract
The long (but not too long) fluorescence lifetime of CdSe semiconductor qua ntum dots was exploited to enhance fluorescence biological imaging contrast and sensitivity by time-gated detection. Significant and selective reducti on of the autofluorescence contribution to the overall image was achieved, and enhancement of the signal-to-background ratio by more than an order of magnitude was demonstrated. (C) 2001 Optical Society of America.