Generation and intermolecular reactions of 2-indolylacyl radicals

Authors
Bennasar, ML Roca, T Griera, R Bosch, J
Citation
Ml. Bennasar et al., Generation and intermolecular reactions of 2-indolylacyl radicals, ORG LETT, 3(11), 2001, pp. 1697-1700
Citations number
24
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANIC LETTERS
ISSN journal
15237060 → ACNP
Volume
3
Issue
11
Year of publication
2001
Pages
1697 - 1700
Database
ISI
SICI code
1523-7060(20010531)3:11<1697:GAIRO2>2.0.ZU;2-A
Abstract
The generation of 2-indolylacyl radicals from the corresponding phenyl sele noesters, aldehydes, and cr keto carboxylic acids and the scope of their pa rticipation in intermolecular addition reactions to carbon-carbon double bo nds have been studied. Whereas the phenyl selenoester method has provided e asy access to a variety of 1,4-dicarbonyl compounds bearing the 2-acylindol e moiety, the glyoxylic acid route has been employed for the preparation of 2-indolyl pyridyl ketones.