Asymmetric synthesis of quaternary alpha-amino phosphonates using sulfinimines

Authors
Davis, FA Lee, S Yan, HX Titus, DD
Citation
Fa. Davis et al., Asymmetric synthesis of quaternary alpha-amino phosphonates using sulfinimines, ORG LETT, 3(11), 2001, pp. 1757-1760
Citations number
41
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANIC LETTERS
ISSN journal
15237060 → ACNP
Volume
3
Issue
11
Year of publication
2001
Pages
1757 - 1760
Database
ISI
SICI code
1523-7060(20010531)3:11<1757:ASOQAP>2.0.ZU;2-Q
Abstract
The addition of lithium diethylphosphonate to enantiopure ketosulfinimines is highly diastereoselective (> 95%), affording the first examples of quate rnary a alkyl ol-amino (arylmethyl)phosphonates.