In large, prospective studies of pregnancy conducted in the 1960s, women re
ported very accurately whether or not they smoked. However, in the 1990s, p
regnant women who smoke are often pressured to reduce or quit smoking, and
the incentive to misreport may be greater than in the past To assess the ac
curacy of reported smoking, the authors compared self-reported smoking with
cotinine in the serum and/or urine of 105 women who participated in the Ca
lcium for Pre-eclampsia Prevention pilot study in 1992. Cotinine confirmed
the report of 84.6% of women who reported smoking and 94.5% of women who de
nied smoking. Those fractions are virtually identical to those obtained in
a pregnancy cohort from the 1960s. nh authors conclude that in the setting
of two obstetrical research studies not specifically focused on smoking, th
e accuracy of self-reported cigarette smoking did not change substantially
from the 1960s to the 1990s.