Numerous studies have shown that anthelminthic treatment can be effective i
n improving growth rates when given to malnourished children with ascariasi
s. Recent investigations have also indicated that Ascaris infections can af
fect mental processing in some school children. Poor socio-economic conditi
ons are among tile key factors linked with higher prevalences of ascariasis
, as are dcfaecation practices, geophagia, cultural differences relating to
personal and food hygiene, occupational necessity, agricultural factors, h
ousing style, social class and gender. Chemotherapy is currently the major
tool used fur the strategic control of ascariasis as a short-term goal. In
the long term, improvements in hygiene and sanitation are thought to aid lo
ng-term control considerably. Targeted treatment, especially when aimed at
schoolchildren, as been a major focus of recent control efforts in some are
as. Universal treatment reaches more people and thus decreases further aggr
egate morbidity, especially in nutritionally vulnerable preschool-age child
ren. Selective treatment requires technical effort to identify heavily infe
cted individuals; acceptance by the community may vary in less educated pop
ulations when some individuals receive treatment and others do trot. Child-
targeted treatment may be more cost-effective than population treatment in
reducing tile number of disease cases and, in high transmission areas, expa
nding coverage of a population can he a more cost-effective strategy than i
ncreasing the frequency of treatment.