A new physiologic monitor for use in the home has been developed and used f
or the Collaborative Home Infant Monitor Evaluation (CHIME). This monitor m
easures infant breathing by respiratory inductance plethysmography and tran
sthoracic impedance; infant electrocardiogram, heart rate and R-R interval;
haemoglobin O-2 saturation of arterial blood at the periphery and sleep po
sition. Monitor signals from a representative sample of 24 subjects from th
e CHIME database were of sufficient quality to be clinically interpreted 91
.7% of the time for the respiratory inductance plethysmograph, 100% for the
ECG, 99.7% for the heart rate and 87% for the 16 subjects of the 24 who us
ed the pulse oximeter: The monitor detected breaths with a sensitivity of 9
6% and a specificity of 65% compared to human scorers. It detected all clin
ically significant bradycardias but identified an additional 737 events whe
re a human scorer did not detect bradycardia. The monitor was considered to
be superior to conventional monitors and, therefore, suitable for the succ
essful conduct of the CHIME study.