Lead and zinc influence on antioxidant enzyme activity and malondialdehydeconcentrations

Authors
Kulikowska-Karpinska, E Moniuszko-Jakoniuk, J
Citation
E. Kulikowska-karpinska et J. Moniuszko-jakoniuk, Lead and zinc influence on antioxidant enzyme activity and malondialdehydeconcentrations, POL J ENV S, 10(3), 2001, pp. 161-165
Citations number
19
Categorie Soggetti
Environment/Ecology
Journal title
POLISH JOURNAL OF ENVIRONMENTAL STUDIES
ISSN journal
12301485 → ACNP
Volume
10
Issue
3
Year of publication
2001
Pages
161 - 165
Database
ISI
SICI code
1230-1485(2001)10:3<161:LAZIOA>2.0.ZU;2-G
Abstract
The influence of zinc on the activity of antioxidant enzymes in the blood o f rats intoxicated with lead was studied. Exposure to lead at the concentra tion of 500 mg/dm(3) for 6 weeks caused a decrease in the activities of SOD , GSH-P-x and GR as well as an increase in MDA concentrations in the serum. Zinc at the concentration of 60 mg/dm(3) administered for a period of 2 we eks after exposure to cadmium reduced the effects of toxic action of lead l eading to a normalization of the activities of SOD and GR in the blood as w ell as MDA concentration in the serum.