The authors report a case of sarcomatoid carcinoma of the prostate in a 49-
year-old patient. The clinical symptoms were dominated by dysuria and frequ
ency. Digital rectal examination showed a very large, hard and irregular pr
ostate. Serum PSA was normal. Transrectal ultrasonography and abdominopelvi
c computed tomography showed a heterogeneous mass occupying the vesico-pros
tatic junction. The patient underwent cystoprostatectomy. Histological exam
ination of the cystoprostatectomy specimen revealed a tumour composed of sp
indle cells expressing epithelial markers on immunohistochemical analysis a
nd concluded on a diagnosis of sarcomatoid carcinoma of the prostate. The p
atient died seven months after cystoprostatectomy.