Ga. Sandison et al., PHANTOM ASSESSMENT OF LUNG DOSE FROM PROTON ARC THERAPY, International journal of radiation oncology, biology, physics, 38(4), 1997, pp. 891-897
Citations number
28
Categorie Soggetti
Oncology,"Radiology,Nuclear Medicine & Medical Imaging
Purpose: To compare resultant lung dose from proton are therapy of the
chest wall to that from electron are therapy, Methods and Materials:
A 200 MeV proton beam from the Indiana University Cyclotron was range
shifted and modulated to provide a spread out Bragg peak extending fro
m the surface to a depth of 4 cm in water, The chest wall of an Alders
on Rando phantom was irradiated by this beam, collimated to a 20 X 4 c
m field size, while it rotated on a platform at approximately 1 rpm, F
or comparison, electron are therapy of the Rando phantom chest wall wa
s similarly performed with 12 MeV electrons and the resultant lung dos
e measured in each case. Results: Dose-volume histograms for the Rando
phantom left lung indicate a reduced volume of irradiated lung for pr
otons at all dose levels and an integral lung dose that is half that f
or electron are therapy in the case studied, In addition, a more unifo
rm dose coverage of the target volume was achieved with the proton the
rapy. Conclusion: This study demonstrates a potential role for proton
are therapy as an alternative to electron are therapy when lung dose m
ust be minimized, (C) 1997 Elsevier Science Inc.