Many efficient structural optimization algorithms require gradient informat
ion. Semi-Analytical (SA) design sensitivities are rattler popular, as they
combine ease of implementation with computational efficiency. For closed-f
illed structures also the effects of internal pressure changes and solubili
ty of the gas in the fluid may be important. Typical examples for which the
se aspects are relevant can be found in packaging, e.g. edible-oil bottles.
The present paper focuses on design sensitivities for such closed-filled s
tructures. The design sensitivities are based on a refined SA formulation f
or the structure, whereas the contribution related to its contents is evalu
ated analytically.