The vast majority of patients developing obstructive jaundice will have an
underlying malignancy. When the etiology of the obstruction cannot be defin
ed prior to operative intervention. identification of a non-malignant proce
ss will occur only subsequent to a major operation. The clinical course of
a patient with complete distal common bile duct obstruction as the result o
f pancreatic heterotopia is discussed. This uncommon diagnosis prompted a r
eview of the literature on this subject enabling this detailed discussion i
nclusive of the embryology, prevalence and clinical presentations of this e
ntity. Our review further identified a varied group of other non-malignant
causes of biliary obstruction that may be mistakenly interpreted to represe
nt biliary or pancreatic malignancy. (C) 2001 Elsevier Science Ltd. All rig
hts reserved.