Obscuraminols, new unsaturated amino alcohols from the tunicate Pseudodistoma obscurum: structure and absolute configuration

Authors
Garrido, L Zubia, E Ortega, MJ Naranjo, S Salva, J
Citation
L. Garrido et al., Obscuraminols, new unsaturated amino alcohols from the tunicate Pseudodistoma obscurum: structure and absolute configuration, TETRAHEDRON, 57(21), 2001, pp. 4579-4588
Citations number
16
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020 → ACNP
Volume
57
Issue
21
Year of publication
2001
Pages
4579 - 4588
Database
ISI
SICI code
0040-4020(20010521)57:21<4579:ONUAAF>2.0.ZU;2-U
Abstract
The study of the ascidian Pseudodistoma obscurum from Tarifa Island (Cadiz, Spain) has led to the characterization of six new unsaturated 2-amino-3-ol compounds, the obscuraminols A-F. Five of them, the obscuraminols B-F, wer e isolated as their corresponding diacetyl derivatives. Their structures we re established by spectroscopic analysis, their relative configurations by NOEDS study of oxazolidinone derivatives, and their absolute configurations by application of Mosher's method to N-acetyl derivatives. (C) 2001 Elsevi er Science Ltd. All rights reserved.