The application of the readily available 1-thio-1,2-O-isopropylidene acetal
(TIA) 6 (four steps from D-mannose) to the synthesis of analogues of KDO i
s illustrated by the preparation of KDO 1, 1-deoxy-beta -KDO 2 and the beta
-C-KDO glycoside 3. (C) 2001 Elsevier Science Ltd. All rights reserved.