The biosynthesis of moenocinol, the lipid part of the moenomycin antibiotics

Authors
Schuricht, U Hennig, L Findeisen, M Welzel, P Arigoni, D
Citation
U. Schuricht et al., The biosynthesis of moenocinol, the lipid part of the moenomycin antibiotics, TETRAHEDR L, 42(23), 2001, pp. 3835-3837
Citations number
10
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
23
Year of publication
2001
Pages
3835 - 3837
Database
ISI
SICI code
0040-4039(20010604)42:23<3835:TBOMTL>2.0.ZU;2-R
Abstract
The C-25 terpenoid moenocinol is suggested to originate from a farnesyl pre cursor and geranyl pyrophosphate. The new mechanism is in accord with all p revious feeding experiments. Feeding of [2,5-C-13(20)]-labeled 1-deoxy-D-xy lulose proves how the two units are joined in the course of the moenucinol biosynthesis. (C) 2001 Published by Elsevier Science Ltd.