Er. Alonso et al., Grob-type fragmentation of N-alkyl-2-cyano-5-bromopiperidines to unsaturated imidoyl cyanides, TETRAHEDR L, 42(23), 2001, pp. 3921-3923
2-Cyano-5-bromopiperidines. derived from the stereoselective addition of cy
anide to 5-bromomethyl-l-pyrrolinium salts, underwent a Grob fragmentation
by reaction with sodium hydride in dimethylformamide, affording unsaturated
imidoyl cyanides. (C) 2001 Elsevier Science Ltd. All rights reserved.