Synthesis of N-arylated oxazolidinones via a palladium catalyzed cross coupling reaction. Application to the synthesis of the antibacterial agent Dup-721

Authors
Madar, DJ Kopecka, H Pireh, D Pease, J Pliushchev, M Sciotti, RJ Wiedeman, PE Djuric, SW
Citation
Dj. Madar et al., Synthesis of N-arylated oxazolidinones via a palladium catalyzed cross coupling reaction. Application to the synthesis of the antibacterial agent Dup-721, TETRAHEDR L, 42(22), 2001, pp. 3681-3684
Citations number
10
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
22
Year of publication
2001
Pages
3681 - 3684
Database
ISI
SICI code
0040-4039(20010528)42:22<3681:SONOVA>2.0.ZU;2-Z
Abstract
A method for the intermolecular coupling of aryl bromides and oxazolidinone s is described. Application to intermediates useful for the preparation of a known class of antibacterial agent and the synthesis of the known antibac terial oxazolidinone Dup-721 are described. (C) 2001 Elsevier Science Ltd. All rights reserved.