Novell stilbenes isolated from the root bark of Ekebergia benguelensis

Authors
Chavez, D Chai, HB Chagwedera, TE Gao, Q Farnsworth, NR Cordell, GA Pezzuto, JM Kinghorn, AD
Citation
D. Chavez et al., Novell stilbenes isolated from the root bark of Ekebergia benguelensis, TETRAHEDR L, 42(22), 2001, pp. 3685-3688
Citations number
12
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
22
Year of publication
2001
Pages
3685 - 3688
Database
ISI
SICI code
0040-4039(20010528)42:22<3685:NSIFTR>2.0.ZU;2-7
Abstract
Four novel stilbenes (1-4) were isolated from the root bark of Ekebergia be nguelensis. The structures were established by spectroscopic methods includ ing 2D NMR analysis. The structure of I, a new stilbene-coumarin hybrid rep resenting a novel skeleton, was confirmed by single X-ray analysis. Compoun ds 1-4 were evaluated against a panel of human cancer cell lines. (C) 2001 Elsevier Science Ltd. All rights reserved.