Synthesis of a C-3-symmetric ferrocenylphosphine and its application to the Suzuki reaction of aryl chlorides

Authors
Pickett, TE Richards, CJ
Citation
Te. Pickett et Cj. Richards, Synthesis of a C-3-symmetric ferrocenylphosphine and its application to the Suzuki reaction of aryl chlorides, TETRAHEDR L, 42(22), 2001, pp. 3767-3769
Citations number
19
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
42
Issue
22
Year of publication
2001
Pages
3767 - 3769
Database
ISI
SICI code
0040-4039(20010528)42:22<3767:SOACFA>2.0.ZU;2-P
Abstract
(S-p,S-p,S-p)-Tris(2-methyl ferrocenyl)phosphine 1 was synthesised in 62% y ield from (S)-2-ferrocenyl-4-(1-methylethyl)oxazoline. In combination with Pd(2)dba(3) this novel C-3-symmetric ligand generates a catalyst for the Su zuki reaction of aryl chloride substrates, these reactions proceed readily at 60 degreesC in dioxane. (C) 2001 Elsevier Science Ltd. All rights reserv ed.