The levels of tetrodotoxin and its analogue 6-epitetrodotoxin in the red-spotted newt, Notophthalmus viridescens

Authors
Yotsu-Yamashita, M Mebs, D
Citation
M. Yotsu-yamashita et D. Mebs, The levels of tetrodotoxin and its analogue 6-epitetrodotoxin in the red-spotted newt, Notophthalmus viridescens, TOXICON, 39(8), 2001, pp. 1261-1263
Citations number
13
Categorie Soggetti
Pharmacology & Toxicology
Journal title
TOXICON
ISSN journal
00410101 → ACNP
Volume
39
Issue
8
Year of publication
2001
Pages
1261 - 1263
Database
ISI
SICI code
0041-0101(200108)39:8<1261:TLOTAI>2.0.ZU;2-H
Abstract
Tetrodotoxin (TTX) and its analogue 6-epiTTX were detected in 11-12 specime ns of the red-spotted newt, Notophthalmus viridescens. by a post-column flu orescent-HPLC system and by LC/MS in selected ion monitoring mode. TTX leve ls varied considerably among individuals from low (less than 0.15 mug TTX/g newt) to high concentrations (23.5 mug TTX/g newt),while 6-epiTTX was foun d to be a minor constituent in all specimens. (C) 2001 Elsevier Science Ltd . All rights reserved.